FORMULATION DEVELOPMENT | FILL-FINISH | STERILE MANUFACTURING | PAT
Homogenizing Perfected: Solutions for Pharma Industry

Kinematica: from Switzerland to the world!

Since the company’s founding in 1962, innovation has been a cornerstone of Kinematica’s development strategy. Ever since the company’s founder, Professor Willems, revolutionized the industry with his rotor / stator invention, Kinematica has continued perfecting the technique by customizing and engineering its solutions to fit the most demanding applications.

Kinematica’s commitment to state-of-the-art technology has remained intact and been renewed decade after decade by achieving a de facto standard in several industries today, where their products are helping thousands of end users around the world.

POLYTRON LABORATORY STAND-DISPERSER(HIGH-END LINE), FLEXIBLE USE BATCH DISPERSING SYSTEM

PT 3100D - Applications with the highest demands for reproducibility and scaling up can be efficiently performed with this device. The fully digitized control and regulation system is very easy to operate. The illuminated LCD display shows all the parameters, which can be changed with the membrane keypad.

Smallest sizes of particles/droplets, Efficient sample preparation, Standard or custom-made aggregates, Cleaning and disassembly, Quick coupling of the aggregates are few best part of the system features.

POLYTRON SERIES PT / PT-C BATCH PILOT/PRODUCTION SIP/CIP COMPATIBLE HIGH SHEAR HOMOGENIZER

POLYTRON PT-C, Batch High Shear homogenizer is most suitable for the pharmaceutical sterile processing when batch dispersion is necessary. The system shall be integrated with wide variety of vessel and the process including CIP and SIP shall be automated.

PT-C shall be offered for the batch size upto 50L for efficient particle/droplet size reduction. Special geometry generators available for specific target application.

Available as standalone or vessel integration ready configuration

THE NEXT GENERATION: NEW INLINE HOMOGENIZING UNIT WITH RECIRCULATING VESSEL FOR SMALL VOLUME PROCESS TRIALS

MEGATRON MT 3100 S2, When testing and optimizing formulas, high process safety is paramount. This system enables processing of complex material systems with absolutely minimal loss of mass and minimal energy. This system was developed to help Realize the ideas under as realistic conditions as possible in small economic quantities. During subsequent scale-up, the results can be replicated with our large machines.

A complete process system with double wall glass vessel, bottom outlet valve, thermometer, piping/direct coupling with inlet flange for working chamber MT 3100 S2

PHARMACEUTICAL STERILE INLINE DISPERSING/HOMOGENIZING SYSTEM

MEGATRON MT SV, The sterile manufacture of pharma, cosmetic, food and life science requires dispersing technology especially designed for process safety and quality. Among these features are high-grade stainless steel materials, approved static and dynamic sealing systems, designs far-reaching free of dead space and with fine surface finishes, SIP and CIP cleaning possibility, and compliance with the required cleanroom classification.

To meet the precise standards for sterile production the MEGATRON® MT-SV series was designed to meet the highest safety and quality standards in accordance with applicable international guidelines and standards.

LAB MICROTRON FOR BOTTOM MOUNTED DISPERSING/HOMOGENIZING

REACTRON RT – MB, The first of its kind compact processing setup for dispersion and homogenization using bottom mounted rotor/stator. Offers superior results when processing variable batch volume especially in laboratory process optimization. Enables seamless tech transfers with the similar scaleup setup exclusively designed by Kinematica for chosen application.

Available in 1L, 2L, 3L and custom size as well. Built in controller enables ease of operation and additional special accessories and instrumentation shall be custom designed.

MICROTRON MB PRODUCTION BOTTOM MOUNTED DISPERSING/HOMOGENIZING

MICROTRON MB-SV, Bottom mounted space saving Dispersing and Homogenizing system for sterile applications in Pharmaceutical process. Configured with complete vessel setup or available as ready to be integrated based on application and process needs.

Ideal for CIP/SIP applications and for the process from small to large volume through ideal positioning in process vessel.

Special design configurations available to meet both process and compliance requirements.

MEGATRON INLINE DISPERSING SYSTEM WITH SUPER HIGH SHEAR FORCES

The newly developed MEGATRON® MT-SHS Pilot Plant unit is able to produce rotor tip speeds of 65m/s and shear rate of 300 000 s-1. This novelty provides six times the shear rate than the ones of our standard product range. Due to the very high energy input it is possible to achieve particle or droplet sizes that go well into the nano range, results vary based on the component system being processed.

Newly developed concept in rotor/stator technology provides the smallest possible particle sizes with the highest efficiency, Rotor tip speeds up to 65m/s possible, Shear rates up to 300 000 s-1 possible, High specific energy input resulting in nano sized particles or droplets (product dependent), Different rotor/stator geometries are available, Scale-up is in preparation up to productions machines.