FORMULATION DEVELOPMENT | FILL-FINISH | STERILE MANUFACTURING | PAT
Pharmaceutical Sterilization, Washing, Decontamination & Process equipment. The First Italian Sterilizer Manufacturer since 1949

De Lama, for over 70 years, has been a world leader in the design and production of high quality sterilizers, with a range that includes saturated steam autoclaves, air-steam mixture sterilizers, superheated water sterilizers, dry heat sterilizers (DHS), Ethylene Oxide (ETO) autoclaves, up to the latest high vacuum Hydrogen Peroxide (H2O2) sterilizers with proprietary HyPerPure® technology which represent the most innovative solution that De Lama is able to provide to treat, in particular, heat-sensitive products (like many medical devices) that could not be processed with more traditional techniques.

The De Lama range is not limited to sterilizers, but also includes state-of-the-art industrial GMP washing machine, dryers and dryers under-vacuum, innovative Hydrogen Peroxide decontamination units (pass-box) and equipment for low temperature treatments.

Vertical Laboratory Autoclave

DLV-CAB Series - The industrial and pharmaceutical top-end technology applied to a compact design and they are suitable for the widest variety of application in the Pharmaceutical Industry.

Available as saturated Steam sterilizer or combination with Air-steam and counter pressure cooling arrangements.

Comes with superior control system with F0 cycle management for specific application and full compliance to 21 CFR part 11.

Saturated Steam Production Sterilizer

De Lama DLOV are the most versatile steam autoclaves designed to meet the widest requirements of the Pharmaceutical Industry. DLOV series autoclaves exploit an extensive operational flexibility enabling their usage for a wide range of industrial applications.

Autoclaves components are of the highest quality and reliability, worldwide available for ease of replacement and to assure the longest equipment lifespan. Chamber is built either in cylindrical or square shape, for horizontal operation. Available configurations range from the basic steam sterilization to the combined air/steam mixture suitable for deformable containers or pre-filled syringes.

Saturated-Steam-Sterilizer
Air/Steam Mixture Production Sterilizer

Air/steam mixture sterilizer DLOAV series was specially designed to perform sterilization treatment of large volume infusion/parenteral solutions packed both in non-deformable containers as well as in containers deformable by differential pressure under heat exposure.

Chamber is built in Cylindrical shape for horizontal operation. Autoclave is suitable even for pasteurization treatment of packed food products. Autoclaves components are of the highest quality and reliability, worldwide available for ease of replacement and to assure the longest equipment lifespan. Standard and customized models and sizes are available.

Air Steam Mixture Sterilizer
Superheated Water Production Sterilizer

De Lama superheated water circulation sterilizers, with spray distribution system, DLOS series, are specially designed to perform sterilization treatment of large volume infusion/parenteral solutions packed both in non-deformable containers as well as in deformable containers able to withstand sterilization conditions by hot water spray. Chamber is available in cylindrical horizontal execution.

De Lama autoclaves components are of the highest quality and reliability, worldwide available for ease of replacement and to assure the longest equipment lifespan. Standard and customized models and sizes are available.

Superheated Water Sterilizers
Combined Washing | Sterilization Autoclave

De Lama sterilizers, in DLOV-W configuration combine the performances of a saturated steam sterilization autoclave, DLOV model, with those of a high-efficiency industrial washing machine useful for components cleaning , machine parts , loading accessories which require the removal of dust residual, particulates and contaminants.

This equipment allows to 1) wash, sterilize and dry with one single process tanks , mechanical parts or other materials 2) reduce number and volumes of the equipment installed in controlled environment 3) reduce validation and maintenance costs 4) simplify staff operational procedures 5) load and unload from the same side of the equipment all those products that are already in a controlled contamination environment.

Combined-Saturated-Steam-Washing
Industrial CGMP Washer for Pharma

The new De Lama DLWM industrial washer, is the result of over 20 years of experience in industrial washing machines for the pharmaceutical sector.

Today all this know-how encompasses a whole range of concepts, improvements and totally innovative details for the sector.

The DLWM is designed for the treatment of all the accessories used in the pharmaceutical, health / hospital sector, in laboratories and research institutes, in the cosmetics and nutraceutical market.

De Lama washers are designed to fully comply with all the principles of ‘Cleaning Validation’ Made in both standard and custom models.

GMP-Washer
Vacuum Hydrogen Peroxide Passbox

De Lama has developed an innovative process starting from many years of experience in the field of sterilization and decontamination: sterilization and decontamination with hydrogen peroxide under vacuum.

The new vacuum hydrogen peroxide decontamination pass-box allows to reach new standards of performance and repeatability for surface decontamination of loads and in particular offers completely new advantages for the sector such as possibility of any chamber size, even very big, no impact on HVAC systems, ultra-fast process, vacuum and pressure tests & No consumables: savings in costs and management times.

GMP-Washer
DHS - Dry Heat Sterilization and Depyrogenation Class

The dry heat sterilizers DLST/L type (Class 100 – ISO 5) are cGMP designed to meet the widest requirements of the Pharmaceutical Industry and to perform following treatments:

Sterilization : reduction of microorganisms and their by-products by up to 12 log (temperature range: 160÷180oC)

Depyrogenation : destruction of pyrogens and endotoxins inside the materials (temperature range: 250÷300oC)

Possibility to foresee oven execution to withstand operating temperatures up to 300°C in continuous service by use of HEPA filters with special sealant. Chamber is available in horizontal execution.

GMP-Washer