Shim-pack Bio Diol and IEX columns improve the accuracy of the characterization of peptides, oligonucleotide and biopharmaceuticals. Shim-pack Bio Diol LC columns are offered in different pore sizes and offer an excellent solution for analysis of aggregates and fragments of mAb, oligonucleotides, and carbohydrates. Columns with reduced particle size from 5 μm to 2 μm to greatly improve the resolution between aggregates and monomers. A 50 percent shorter run time while maintaining resolution can be achieved using a 2 μm particle sized column.

Shim-pack Bio Diol Diol-60 Diol-120 Diol-200 Diol-300
Particle Silica
Ligand Dihydroxypropyl(Diol)
Particle Size 3 μm, 5 μm 2 μm, 3 μm, 5 μm
Pore Size 6 nm 12 nm 20 nm 30 nm
pH Range 5.0 - 7.5
Molecular Weight Range below 10,000 1,000 - 100,000 5,000 - 300,000 20,000 - 1,000,000