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VISTA Oxygen Inspection Machine

The VISTA Headspace Inspection platform is an automated in-line 100% inspection machine designed to simultaneously monitor oxygen, pressure, and moisture levels in sealed parenteral containers. The patented machine platform was originally developed with funding from the Food and Drug Administration and received the 2004 Parenteral Drug Association New Innovative Technology Award.

The automated headspace machine platform can be configured for headspace oxygen inspection only. The VISTA/O In-Line Oxygen Inspection System is an ‘in-line, 100% inspection and rejection system’ designed to monitor oxygen levels in sealed parenteral containers. The VISTA/O System is capable of directly measuring oxygen concentrations in the headspace of optically transparent packages stoppered under an inert atmosphere (nitrogen, argon). Up to four oxygen sensors can be mounted on the machine depending on the required line speed and sensitivity.

Applications include leak testing of lyophilized and liquid product, and purge performance monitoring during the filling of oxygen-sensitive product, In-process monitoring of headspace oxygen levels in parenteral containers, container closure integrity testing in pre-filled syringes etc. The non-destructive nature of the measurement enables a full statistical documentation of system performance.

  • Measurement Range : 0 to 21% (oxygen)
  • Throughput : 200 vials per minute
  • Container sizes : 1 to 200 ml
  • Container Compatibility : Tubing or molded; amber or clear
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VISTA Oxygen Inspection Machine