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N-Series Ultra High Performance Liquid Chromatograph

Building upon 40 years of experience in LC technology, the N-Series UHPLC blends cutting edge AI and IoT enhancements to set new industry benchmark.

The N-Series UHPLC has been designed to meet new customer challenges and requirements. A marriage of the Shimadzu LC's outstanding hardware performance and the latest digital technologies such as IoT and M2M brings us to achieve the “highly reliable data acquisition" with "improvement of operational efficiency" based on the following three maxims. With the aim of becoming a new industry standard, Shimadzu has brought in a new experience of LC analysis.

A New Benchmark of Intelligence

New functionalities for Analytical Intelligence (AI). A variety of automated features that support analytical workflows help improve reliability and efficiency.

A New Benchmark of Design

It further advances the outstanding hardware performance which is the basis of Shimadzu LC and strongly supports the improvement of data reliability.

A New Benchmark of Efficiency

Ultra-high speed injection performance on the autosampler and a large sample capacity of the PLATE CHANGER accelerate ultra-high throughput analysis.


Fully Unattended Operation from Startup to Shutdown
N-Series UHPLC can be set to start up at a specified time, so that it can complete auto-purge, equilibration and baseline checks in advance, and be ready for analysis as soon as you arrive at the lab. Moreover , the system can be set up in advance to run without user intervention all the way from start up through analysis to shutdown

Auto-Diagnostics and Recovery
N-Series UHPLC has the ability to monitor baseline changes and pressure fluctuations to check for abnormalities. When it detects an unusual fluctuation, it can automatically pause the analysis, purge the flow path, and restart analysis once it has confirmed recovery to normal pressure.

FlowPilot Protects Columns
HPLC columns can be damaged by sudden pump starts and stops or extreme gradient changes. The N-Series UHPLC automatically uses FlowPilot (Smart Flow Control) to increase the flow rate gradually to the set point. There is no need to create startup protocols for each analysis.(Pat. Pending)

Mobile Phase Levels Measured in Real Time
Reservoir tray weight sensors (optional) can be used to monitor the volume of mobile phase or autosampler rinse solution in up to twelve containers. The containers can also be checked remotely from a smart device. You will no longer need to worry about running out of mobile phase mid-analysis, because the device will notify you before starting the run if the volume remaining is too low.

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