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DAWN® HELEOS® II Static Light Scattering Detector

The world's most advanced MALS instrument for characterization of macromolecules and nanoparticles in solution to determine absolute molar mass and size.

The DAWN® HELEOS® II is the premier Multi-Angle static Light Scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution, offering the highest sensitivity and widest range of molecular weight, size and concentrations. It is most often used in conjunction with Size Exclusion Chromatography (SEC-MALS) or Field-Flow Fractionation (FFF-MALS) to determine distributions of mass, size and composition independent of column calibration by reference standards.

Included with each DAWN® is a copy of ASTRA, the most versatile software package available for analysis of online multi-angle and dynamic light scattering.The DAWN® HELEOS® II and its companion Optilab T-rEXdRI detector are the established benchmarks for MALS analysis, cited in thousands of peer-reviewed publications. With the addition of a ViscoStar II differential viscometer or WyattQELS DLS module, the triple-detection system can analyze molecular conformation and sizes below the rg limit of 10 nm.The DAWN® may also be used in batch (off-line) mode to characterize the weight-average molar mass, z-average size and second virial coefficient of unfractionated samples.

  • The gold standard for absolute molar mass and size
  • Mw from 200 Da to 1000 MDa
  • Sensitivity: 0.4 µg/mL BSA (66.4 kDa)
  • rg from 10 to 500 nm, up to 1000 nm with shape-specific models
  • Ultra-stable, high-power laser
  • Superior technology and productivity
  • Endorsed by the scientific community
  • Compatible with any HPLC system
  • Integrated COMET ultrasonic device automates in situ cell cleaning
  • Decades of experience in MALS technology
  • Power Industry-standard ASTRA software
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DAWN® HELEOS® II
Static Light Scattering Detector

Featured Applications