The new Sequel System is based on PacBio’s proven Single Molecule, Real-Time (SMRT) technology and delivers about 7X more reads with 1 million zero-mode waveguides (ZMWs) per SMRT Cell. SMRT® technology is built upon two key innovations that overcome major challenges in the field of sequencing. Zero Mode Waveguides(ZMW) allow light to illuminate only the bottom of a well in which a DNA polymerase/template complex is immobilized. Phospholinked nucleotides allow observation of the immobilized complex as the DNA polymerase produces a completely natural DNA strand. The Sequel System is ideal for projects such as rapidly and cost-effectively generating high-quality whole genome de novo assemblies.
The innovative sequencing system features automated reagent and SMRT Cell handling and an integrated software suite. Additional features of the Sequel System include: Intuitive run setup and monitoring tools; Run-time flexibility (from 30 minutes to 10 hours per SMRT Cell); Run-size flexibility (from 1 to 16 SMRT Cells per run); Robotic workflow management
Gain a Comprehensive View of Genomics, Transcriptomes and Epigenomes