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SpectraMax M Series Multimode Microplate Reader

Every SpectraMax® M Series Multi-Mode Microplate Reader does UV and visible absorbance, and fluorescence intensity measurements on microplates and cuvettes. One can choose one that adds glow luminescence, time-resolved fluorescence, fluorescence polarization, or, in the case Molecular Devices’ top-of-the-line M5e, all of these, plus HTRF.

All M Series readers accept cuvettes and 6-, 12-, 24-, 48-, 96-, and 384-well microplates. Other standard features include spectral scanning across the wavelength range in 1 nm increments, up to six absorbance wavelengths per read, and up to four wavelength pairs for other read modes.

Patented AutoPMT Optimization System

The patented AutoPMT optimization system of the SpectraMax M5 Microplate Reader adjusts the fluorescence detector to each sample well's concentration and normalizes the raw data, extending the dynamic range of assays so that low, medium, and high signals can be captured from the same plate. This calibration against an internal standard provides an additional benefit in being able to confidently compare relative fluorescence units (RFUs) of individual samples across plates and readers.

Patented PathCheckPathlength Measurement Technology

Offers the capability to measure the depth (optical pathlength) of samples in a temperature independent manner using the patented PathCheck® Technology. With SoftMax Pro® Software, the PathCheck Technology automatically normalizes the well absorbance

Comprehensive Reader Validation

Molecular Devices microplate readers have the most complete level of product validation and compliance of any system on the market. A variety of tools are available to users to meet users' diverse validation needs. Molecular Devices provides the complete solution covering the instrument and software.

Industry Leading Software

SoftMax® Pro Data Acquisition & Analysis Software offers:

  • The most extensive library of ‘Ready-to-Run’ application protocols
  • Optional tools for regulated labs with SoftMax Pro GxP Compliance Software
  • Advanced calculations including non-linear fitting metrics for in-depth analysis
  • The only Mac- and Windows-native application support for seamless exchange of data files between operating systems
  • Proven integrations with leading automation and LIMS platforms
  • Pre-written SpectraDrop™ Plate protocols enabling micro volume applications measurements
  • Seamless integration with StakMax® Microplate Handling Stacker
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